An analysis of a mathematical model describing the growth of a tumor treated with chemotherapy
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Oct 28, 2020
About this article
Published Online: Oct 28, 2020
Page range: 185 - 204
Received: Sep 04, 2019
Accepted: Feb 07, 2019
DOI: https://doi.org/10.2478/amns.2020.2.00037
Keywords
© 2020 Anderson L. A. de Araujo et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.
We present a mathematical analysis of a mixed ODE-PDE model describing the spatial distribution and temporal evolution of tumor and normal cells within a tissue subject to the effects of a chemotherapeutic drug. The model assumes that the influx of chemotherapy is restricted to a limited region of the tissue, mimicking a blood vessel passing transversely. We provide results on the existence and uniqueness of the model solution and numerical simulations illustrating different model behaviors.